This talk introduces a scalable Operational Design Domain (ODD) based safety assurance framework for Automated Driving Systems. The framework involves three key phases: scenarios; environment and safety argument. The talk will focus on how each phase can be developed as a function of ODD while focussing on tools and standards which are enabling this workflow and addressing SOTIF needs. The talk will introduce the Safety PoolTM Scenario Database (world’s largest public scenario database for automated driving systems) which enables test engineers, developers, regulators, and policy makers to seamlessly link ODD definition with test scenarios and corresponding metrics for “safe enough”.